Agilent Genomics
  Agilent Cytogenetic Microarrays Solutions
   
 
Human Genome CGH+SNP Microarrays

Capture copy number changes as well as copy neutral aberrations, such as loss of heterozygosity (LOH) and uniparental disomy (UPD), with Agilent's SurePrint G3 CGH+SNP microarrays. Use the same protocol as the standard CGH workflow and maintain the high-resolution quality achieved with CGH-only microarrays. Probe design and selection have been carefully optimized and validated for maximal sensitivity and specificity.
 
 
Detect copy number changes and LOH/UPD on a single microarray
Probes annotated against NCBI Build 37 (UCSC hg19, February 2009)
Format-dependent overall median probe spacing
0.5 μg total genomic DNA input requirement
Slide format depends on microarray. Can be purchased as a kit of five (2x400K) or as a kit of three (4x180K).
Slide format depends on microarray. Can be purchased as a kit of five (2x400K), a kit of three (4x180K) or as a bundle together with reagents and consumables.
   
   
  SurePrint G3 Custom CGH+SNP microarrays allow high-throughput, high-resolution profiling of DNA copy number and copy neutral aberrations, such as loss of heterozygosity (LOH) and uniparental disomy (UPD). Using probes of your choice, design your own custom CGH+SNP microarrays with eArray; Agilent's online array design application.
   
 
Probe design and selection have been carefully optimized and validated for maximal sensitivity and specificity
Genome-wide design or zoom-in designs available for unparalleled resolution, flexibility, and convenience
Multiple formats - SurePrint G3: 1x1m, 2x400k, 4x180k, 8x60k
Current content source database includes over 28 million predesigned, in silico-validated human CGH probes that span exonic, intronic, intergenic,CNV, pseudoautosomal, and segmented duplication DNA regions, and SNP probes for ~65,000 SNPs
Customizable number of slides per kit
   
   
  The Agilent Human Genome CGH Microarray is a high-resolution tool for genome-wide DNA copy number variation profiling without amplification or complexity reduction. Comprehensive probe coverage is enhanced with emphasis on known genes, promoters, miRNAs, pseudoautosomal, and telomeric regions.
   
 
Coding and non-coding human sequences represented
Probes annotated against NCBI Build 37 (UCSC hg19, February 2009)
Probes on the ISCA microarrays were chosen in partnership with the International Standards for Cytogenomic Arrays Consortium
Format-dependent overall median probe spacing
0.5 μg total genomic DNA input requirement
All slide formats printed using Agilent's 60-mer SurePrint technology
Slide format depends on microarray. Can be purchased as a kit of five (1x1M, 1x244K and 2x105K), or as a kit of three (4x180K) or as a single slide. or as a bundle together with reagents and consumables.
   
   
  SurePrint G3 or High-Definition Custom CGH microarrays allow high-throughput, high-resolution profiling of DNA copy number. Using probes of your choice, design your own custom CGH microarrays with Agilent's eArray online array creation application tool.
   
 
Design your own custom microarrays at no cost with Agilent's eArray application
Current content source databases include human, mouse, and rat - over 24 million predesigned, in silico-validated CGH probes that span exonic, intronic, intergenic, CNV, pseudoautosomal, and segmented duplication DNA regions.
Probe design and selection have been carefully optimized and validated for maximal sensitivity and specificity
Genome-wide design or zoom-in designs available for unparalleled resolution, flexibility, and convenience
Multiple formats - High-Definition: 1x244K, 2x105K, 4x44K, and 8x15K; SurePrint G3: 1x1M, 2x400K, 4x180K, 8x60K
Printed using Agilent's 60-mer SurePrint technology
Customizable number of slides per kit
   
   
  The Agilent Model Organism Genome CGH Microarray brings optimal clarity to comparative genomic hybridization by enabling researchers to perform ultra high resolution, genome-wide DNA variation profiling without amplification or complexity reduction.
   
 
Coding and non-coding sequences represented
Format-dependent overall median probe spacing
Probes annotated against indicated sources
0.5 μg total genomic DNA input requirement
Slide formats printed using Agilent's 60-mer SurePrint technology
Available as a single slide.
   
   
  Agilent SurePrint G3 and High-definition CNV microarrays enable multiple loci to be assessed simultaneously, allowing for their identification and characterization. The microarrays provide high-resolution and optimized probe design for maximal sensitivity and specificity as required by the researcher.
   
 
Coding and non-coding human sequences represented
Probes annotated against UCSC hg18 (NCBI Build 36, March 2006)
Format-dependent overall median probe spacing
0.5 μg total genomic DNA input requirement
All slide formats printed using Agilent's 60-mer SurePrint technology
Slides per kit determined by microarray format
   
   
  eArray

eArray is a web-based application that enables you to harness the flexibility of Agilent's SurePrint oligo manufacturing technology in the creation of custom microarray designs and oligo libraries. eArray, free to all registered users, allows you to create assays that are specific to your research needs.
   
 
Create custom microarray designs for Gene Expression, microRNA, Model Organisms, CGH, ChiP-on-chip,and DNA Methylation.
Create custom libraries for SureSelect Target Enrichment applications.
Search and select probe content from our High Definition CGH and Location Analysis Databases.
Add Agilent catalog content to your custom microarray designs.
Design your own format through various layouts, from 8 x 15k up to 1 x 1m.
Enable collaborations by sharing and publishing designs with other researchers
   
   
 
Agilent CytoGenomics

Agilent CytoGenomics software is a complete CGH and CGH+SNP microarray data analysis and data reporting solution. Agilent CytoGenomics provides full support for efficient analysis and data reporting of cytogenetic samples using both information from the CytoGenomics in-house database and external databases such as OMIM, DGV and Entrez. With this new software, Agilent Technologies provides a statistically and visually powerful tool to streamline the day-to-day cytogenetic sample analysis research workflow.

Agilent CytoGenomics supports analysis of data generated from Agilent CGH and CGH+SNP microarrays. For CGH analysis the software supports constitutional samples and genetically complex samples such as hematological and solid cancer samples, including mosaic samples. For CGH+SNP analysis, Agilent CytoGenomics supports constitutional samples and genetically complex samples such as hematological cancer samples, including mosaic samples.
 
   
 
Compare data to external databases, including OMIM and DGV
Search and compare with your in-house database
Automate TIFF image upload, feature extraction and analysis
Generate custom reports
Perform streamlined analysis of normal constitutional samples in < 5 minutes
   
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