HPLC - Polaris Columns  

In areas like drug discovery where target compounds are increasingly polar, it is critical to have a reversed phase column that performs well under aqueous conditions. Retention is critical, but cannot caome with trouble some secondary interactions.

From the collapse-resistant pore structure of our base silica, to the "wettability" engineered into the bonded phases, Polaris columns have been designed for high aqueous conditions. The combination of high phase density bonding, ultra pure silica & silanol shielding leads to excellent peak shape among polar modified columns.
Plaris offers a variety of polar modifications in both C18 and C8 chemistries

Polaris C18-A: The best starting place for separations where the benefits of polar-modified columns are desired. The polar modifications of C18-A help it avoid poor peak shape and retention issues in low organic conditions.

Polaris C8-A: Offers an alternative selectivity to standard C8 phases ans has a lower hydrophobicity than Polaris C18-A, ideal for polar samples, or faster overall analysis times.

Polaris C18-Ether: Offers an alternative selectivity to Polaris C18-A and standard C18 phases, and delivers increased retention of polar compounds away from the void volume.

Polaris C8-Ether: Offers an alternative selectivity to Polaris C18-A with particular utility for hydrogen bonding compunds.
- Excellent chromatography with mixtures of polar and nonpolar analytes
- Various unique selectivities
- Resilient Polaris NH2 phase offers rapid analysis of carbohydrates and extended lifetime compared to other NH2 phases
 Bonded Phase  Pore Size  Surface Area  Carbon Load  Endcapped  Pore Volume  Ligand Coverage  USP Designation
 Polaris C18-A  180 Å  200 m2/g   13.80%  Yes  1.1 cm3/g  3.9 µmol/m2  L1
 Polaris C8-A  180 Å  200 m2/g  7.40%  Yes  1.1 cm3/g  4.8 µmol/m2  L7
 Polaris C18-Ether  180 Å  200 m2/g  12.10%  Yes  1.1 cm3/g  3.3 µmol/m2  L1
 Polaris C8-Ether  180 Å  200 m2/g  7.10%  Yes  1.1 cm3/g  4.5 µmol/m2  L7
 Polaris C18-Amide  180 Å  200 m2/g  15%  Yes  1.1 cm3/g  4.4 µmol/m2  L60
 Polaris NH2  180 Å  200 m2/g  5.50%  Amide  1.1 cm3/g  3.8 µmol/m2  L8
 Polaris Si-A  180 Å  200 m2/g  N/A  N/A  1.1 cm3/g  N/A  L3
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